Once you’ve installed Symphony I/O software and restarted your Mac, the dialog box shown below appears. Click Yes to use Symphony I/O for sound input and output for applications such as iTunes, Quicktime and other audio utilities.
When the audio interface mode is set to USB Audio, Symphony I/O appears as Symphony I/O : USB Audio

Symphony I/O may be selected for Mac Sound I/O in Audio MIDI Setup.
1. To open Audio MIDI Setup, choose Applications > Utilities > Audio MIDI Setup.
2. In AMS, choose Window > Show Audio Window.
3. In the left hand Devices column, select Symphony 64 (or Symphony I/O : USB Audio when audio interface mode is set to USB Audio).
4. Set Clock Source to the desired source.
5. Ensure that Source is set to PC Card 1, Port 1 (Chs 1-32).
6. Set Format to the desired sample rate. If Logic Pro is open, the sample rate of the session overrides the Format setting.

Symphony I/O may be selected for Mac Sound I/O in the OS X Sound Preferences.
1. Choose Apple > System Preferences and click Sound.
2. Click Output.
3. Select Symphony64: PCI Card 1, Port 1 (Chs 1-32).
4. Click Input.
5. Select Symphony64: PCI Card 1, Port 1 (Chs 1-32).
