If you’re using Skype for Windows with an Apogee USB interface and see the message “Your mic isn’t working. Try another one”, this most likely indicates a sample rate mismatch in the Windows Sound Control Panel.

Ensure the selected sample rate is the same in these two locations.

  1. Control Panel > Sound > Playback > (Select Apogee Interface) > Properties > Advanced
  2. Control Panel > Sound > Recording > (Select Apogee Interface) > Properties > Advanced

See this Knowledgebase post for more details:

http://www.apogeedigital.com/knowledgebase/windows/configure-windows-computer-play-youtube-spotify-audio-via-apogee-interface/